REGIO- AND STEREOSELECTIVE FUNCTIONALIZATIONS OF THE WIELAND-MIESCHER KETONE DERIVATIVES AT THE C-8 POSITION

Takeshi SHIMIZU; Sayoko HIRANUMA; Hirosuke YOSHIOKA

doi:10.1248/cpb.37.1963

著者情報

キーワード: Wieland-Miescher ketone, Kirk-Petrow reaction, phenylthiomethylation, hydroxylation, hydroxymethylation, thiophenylation

ジャーナルフリー

1989 年 37 巻 7 号 p. 1963-1965

DOI https://doi.org/10.1248/cpb.37.1963

詳細

抄録

New efficient methods for stereoselective hydroxymethylation, hydroxylation, and thiophenylation at the C-8 position of the Wieland-Miescher ketone derivatives (2__--4__-) have been developed by diverse modifications from the Kirk-Petrow reaction, which involve autoxidation for the hydroxylation.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）