Mass Spectra of Stereoisomers of 3-Piperidinocyclohexanol Derivatives

Abstract

The mas spectra of 3-piperidinocyclohexanol derivatives (1-6) were measured by electron impact ionization.Characteristic fragment ions were observerd at [M-43]⁺, m/z 182, m/z 164, m/z 140, 138, m/z 124, m/z 111, m/z 98, m/z 85 and m/z 84.The cis- and trans-configurations of 3-piperidinocyclohexanol derivatives could be distinguished by the peak intensities at m/z 140 and m/z 85. The difference between alkyl and phenyl substituents could be recognized from the peak intensities at m/z 182 and m/z 164.