Convenient Synthesis of Stable Sulfur Ylides by Reaction of Active Methylene Compounds with Corey-Kim Reagent

Sadamu KATAYAMA; Toshio WATANABE; Masashige YAMAUCHI

doi:10.1248/cpb.38.3314

Sadamu KATAYAMA, Toshio WATANABE, Masashige YAMAUCHI

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Keywords: stable sulfur ylide, active methylene compound, Corey-Kim reagent, electron withdrawing group, acid-labile functional group, ylidation, ylide-carbon signal, ^<13>C-NMR, long-range ¹³C-¹³C coupling, coupling constant

JOURNAL FREE ACCESS

1990 Volume 38 Issue 12 Pages 3314-3316

DOI https://doi.org/10.1248/cpb.38.3314

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Abstract

A new preparation method for a variety of stable sulfur ylides is described. Reactions of the Corey-Kim reagent with active methylene compounds having two electron withdrawing groups in the presence of triethylamine afforded stable surfur ylides in satisfactory yields.

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