Purines. XL. : Preparation of 9-(ω-Carboxyalkyl)-3-methyladenines

Tozo FUJII; Tohru SAITO; Yukinari KUMAZAWA

doi:10.1248/cpb.38.1392

著者情報

キーワード: 3, 9-disubstituted adenine, 9-substituted adenine 1-oxide, N-oxide O-methylation, 9-substituted 1-alkoxyadenine, adenine ring fission, formamido group N-methylation, alkaline hydrolysis, hydrogenolytic dealkoxylation, amidine formamido cyclization

ジャーナルフリー

1990 年 38 巻 5 号 p. 1392-1395

DOI https://doi.org/10.1248/cpb.38.1392

詳細

抄録

With a view to supplying haptens to be connected to carrier proteins for raising antibodies to 3-methyl-2'-deoxyadenosine (1) and/or 3-methyladenine (3), (3-methyl-9-adenyl)acetic acid hydrochloride (15a) and 4-(3-methyl-9-adenyl)butyric acid hydrochloride (15b) have been prepared from 1-alkoxy-9-(ω-carboxyalkyl)adenine salts (7a and 7b) through the intermediates 11a, b, 12a, b, 13a, b, and 14a, b.

責任著者(Corresponding author)

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