ISOLATION OF NEW SAPONINS FROM THE ROOT OF BUPLEURUM FALCATUM L.

Naobumi EBATA; Kaoru NAKAJIMA; Heihachiro TAGUCHI; Hiroshi MITSUHASHI

doi:10.1248/cpb.38.1432

Naobumi EBATA, Kaoru NAKAJIMA, Heihachiro TAGUCHI, Hiroshi MITSUHASHI

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Keywords: Bupleuri Radix, Bupleurum falcatum, Umbelliferae, malonylsaikosaponin, malonic acid, saikosaponin, oleanane-type triterpene oligoglycoside

JOURNAL FREE ACCESS

1990 Volume 38 Issue 5 Pages 1432-1434

DOI https://doi.org/10.1248/cpb.38.1432

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Abstract

Two new malonylated oleanane-type triterpene oligoglycosides, named malonylsaikosaponins a (1) and d (2), were isolated from Bupleuri Radix, the root of Bupleurum falcatum L. Their structures were elucidated on the basis of the chemical and spectroscopic studies. Quantitative analysis of various Bupleuri Radixes by HPLC suggested that these malonylsaikosaponins are genuine saponins of this crude drug.

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