Further Examination on the Structure of an Alkali-SOluble Glucan Isolated from Omphalia lapidescens : Studies on Fungal Polysaccharide. XXXVI

Abstract

Analytical data of Smith-type degradation products and carbon-13 nuclear magnetic resonance spectroscopy of an alkali-soluble glucan, OL-2, which was isolated from a crude fungal drug "Leiwan" (Omphalia lapidescens), suggested that OL-2 was a β-1, 3-D-glucan possessing approximately two branches at every three main chain glucosyl unit at each C-6 position. Antitumor activities of OL-2 and the degradation product, OR-OL-2c, against the solid form of sarcoma 180 in ICR mice were negative.