Synthesis of (±)-Heritol, a Sesquiterpene Lactone belonging to the Aromatic Cadinane Group

Hiroshi IRIE; Ritsuko MATSUMOTO; Masataka NISHIMURA; Yong ZHANG

doi:10.1248/cpb.38.1852

Hiroshi IRIE, Ritsuko MATSUMOTO, Masataka NISHIMURA, Yong ZHANG

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Keywords: heritol, sesquiterpene lactone, intramolecular Wadsworth-Emmons reaction, butenolide, α-hydroxyketone, Arndt-Eistert reaction

JOURNAL FREE ACCESS

1990 Volume 38 Issue 7 Pages 1852-1856

DOI https://doi.org/10.1248/cpb.38.1852

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Abstract

A synthesis of (±)-heritol, a sesquiterpene lactone, was accomplished starting from methyl 3-methoxy-4-methylbenzoate using an intarmolecular Witting reaction as a key reaction for constructing the butenolide ring.

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