Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Isolation of Two New Coumarin Glycosides from Notopterygium forbesii and Evaluation of a Chinese Crude Drug, Qiang-Huo, the Underground Parts of N. incisum and N. forbesii, by High-Performance Liquid Chromatography
顧 哲明張 徳喜楊 秀偉服部 征雄難波 恒雄
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1990 年 38 巻 9 号 p. 2498-2502

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From the ether extract of the underground part of Notopterygium forbesii, two new coumarin glycosides, bergaptol-O-β-D-glucopyranoside and 6'-O-trans-feruloylnodakenin, were isolated along with known compounds including seven furanocoumarins, two dihydrofuranocoumarins, a sterol glucoside and two phenolic compounds. Analysis of their contents by high-performance liquid chromatography (HPLC) revealed that the underground part of N. forbesii contained large amounts of p-hydroxyphenethyl anisate (0.7%), bergaptol glucoside (0.2%), nodakenin (2%) and 6'-O-trans-feruloylnodakenin (0.7%) and a lesser amount of notopterol (0.08%), while that of N. incisum contained a large amount of notopterol (1.2%) and less amounts of the others. The characteristic difference in chemical composition between the two species enabled us to identify the respective botanical sources of a Chinese crude drug, Qiang-huo derived from N. incisum and N. forbesii by HPLC.

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