A Convenient One-Pot Preparation of Nitriles from Aldoximes Using 2, 2'-Oxalyldi(o-sulfobenzimide)

Tokujiro KITAGAWA; Megumi KAWAGUCHI; Keiko IWASAKI

doi:10.1248/cpb.38.2583

著者情報

キーワード: dehydration, 1, 1'-carbonyldimiidazole, aldoxime, nitrile, 1, 1'-oxalyldiimidazole, saccharin, oxalyl derivative, condensing reagent, dehydrating reagent

ジャーナルフリー

1990 年 38 巻 9 号 p. 2583-2585

DOI https://doi.org/10.1248/cpb.38.2583

詳細

抄録

Under essentially neutral conditions, alkyl, aryl, and heteroaryl aldoximes (4) readily react with 2, 2'-oxalyldi(o-sulfobenzimide) (ODS; 6) in refluxing acetonitrile to give the corresponding nitriles (5) in good yields.

責任著者(Corresponding author)

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