Biological Resolution of (2RS)-Tocopherol and (2RS)-Tocopheryl Acetate

Tetsuo SAKAMOTO; Kenichi TOMITA; Mitsuo YANAGI; Tatsuya OZAWA; Masahiro KAJIWARA

doi:10.1248/cpb.39.130

坂本哲夫, 富田健一, 柳光男, 尾沢達也, 梶原正宏

著者情報

キーワード: biological resolution, (2R, 4'R, 8'R)-α-tocopherol, (2R, 4'R, 8'R)-α-tocopheryl acetate, Mycobacterium B-142, CD

ジャーナルフリー

1991 年 39 巻 1 号 p. 130-132

DOI https://doi.org/10.1248/cpb.39.130

詳細

抄録

Cells of Mycobacterium B-142 have been shown to incorporate (2R, 4'R, 8'R)-α-tocopherol selectively from a mixture of C-2 diasteromers. (2R, 4'R, 8'R)-α-Tocopheryl acetate was isolated from the bacterial cells while the (2S, 4'R, 8'R) isomer was extracted from the culture medium. The method has been extended to other tocopherol diastereomers.

責任著者(Corresponding author)

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