Synthesis of Malabaricones, Diarylnonanoids Occurring in Myristicaceous Plants

Yoshisuke TSUDA; Shinzo HOSOI; Yorii GOTO

doi:10.1248/cpb.39.18

Yoshisuke TSUDA, Shinzo HOSOI, Yorii GOTO

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Keywords: malabaricone, diarylnonanoid, Myristicaceae, synthesis, 6-benzyloxyhexyltriphenyl phosphonium bromide, Witting reaction, crossed aldol reaction, dehydration

JOURNAL FREE ACCESS

1991 Volume 39 Issue 1 Pages 18-22

DOI https://doi.org/10.1248/cpb.39.18

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Abstract

Naturally occurring diarylnonanoids, malabaricones A, B, C, D, and 1-(2-hydroxy-6-methoxyphenyl)-9-(3, 4-methylenedioxyphenyl)-nonan-1-one were synthesized from a common intermediate, 6-benzyloxyhexyltriphenyl phosphonium bromide, by use of the Witting reaction and crossed aldol reaction as key steps.

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