Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Conjugated Nitriles. VI. Reaction of 2-Methylquinoline and Related Compounds with Acyl Cyanides
Masanori SAKAMOTO, Mitsuaki ABE, Keitaro ISHII
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Keywords: azine ring, azole ring, azoline ring, benzoyl cyanide, 4-nitrobenzoyl cyanide, C-acylation, cyanohydrin
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1991 Volume 39 Issue 2 Pages 277-281

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Abstract
The reactions of 2-methylquinoline (7), 2-methylbenzothiazole (25), and related compounds 8-11 and 26-30 with benzoyl cyanide (1) or 4-nitrobenzoyl cyanide (2) proceeded via the cyanohydrin derivatives to afford the corresponding C-acylated products 12-17 and 31-36.
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© The Pharmaceutical Society of Japan
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