NEW SYNTHESIS OF 2-THIO-PAF AND RELATED COMPOUNDS AS SUBSTRATES OF PAF ACETYLHYDROLASE AND PHOSPHOLIPASE A2

Masakazu MURATA; Shigekazu IKOMA; Kazuo ACHIWA

doi:10.1248/cpb.39.1335

NEW SYNTHESIS OF 2-THIO-PAF AND RELATED COMPOUNDS AS SUBSTRATES OF PAF ACETYLHYDROLASE AND PHOSPHOLIPASE A₂

Masakazu MURATA, Shigekazu IKOMA, Kazuo ACHIWA

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Keywords: 2-thio-PAF, PAF acetylhydrolase, phospholipase A₂, arachidonic acid, octanoic acid, stereoselective synthesis

JOURNAL FREE ACCESS

1991 Volume 39 Issue 5 Pages 1335-1336

DOI https://doi.org/10.1248/cpb.39.1335

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Abstract

2-Thio-PAF and related compounds (1a-c) as substrates of PAF acetylhydrolase and phospholipase A₂ were synthesized stereoselectively from optically active 2-O-benzylglycerol monoacetate.

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