Labdane-Type Diterpene Glycosides From Fruits of Rubus foliolosus

Abstract

From fruits of Rubus foliolosus (Rosaceae), a traditional medicine used in Yunnan, China, seven labdane-type diterpene glycosides were isolated. Of these glycosides, five were identified as goshonosides-F1-5 (1-5) which have been isolated from leaves of R. chingii. Structures of two new glycosides, goshonosides-F6 (6) and -F7 (8), were elucidated as α-L-arabinofuranosyl-(1→6)-β-D-glucopyranoside of 13(E)-ent-labda-8(17), 13-diene-3β, 15, 18-triol and 3β, 15-di-O-β-D-glucopyranoside of 13(E)-ent-labda-8(17), 13-diene-3β, 15-diol. Goshonosides-F6 (6) and -F7 (8) were also isolated from the leaves of R. chingii.