Synthetic Studies on Naturally Occurring Coumarins. II. Synthesis of 6, 7-Dimethoxy- and 7, 8-Dimethoxy-5-[(E)-3-oxo-1-butenyl]coumarins

Hisashi ISHII; Tsutomu ISHIKAWA; Hisaya WADA; Hidetoshi MIYAZAKI; Yasuko KANEKO; Takashi HARAYAMA

doi:10.1248/cpb.40.2614

石井永, 石川勉, 和田久弥, 宮崎秀敏, 金子泰子, 原山尚

著者情報

キーワード: Reisch's coumarin, 5-methoxysuberenon, toddalenone, Claisen rearrangement, aryl propargyl ether, 2-methylbenzofuran, masked salicylaldehyde, coumarin synthesis

ジャーナルフリー

1992 年 40 巻 10 号 p. 2614-2619

DOI https://doi.org/10.1248/cpb.40.2614

詳細

抄録

In connection with studies on the structure elucidation of the so-called Reisch's coumarin isolated from Toddalia asiatica, syntheses of two coumarins (4 and 5) were accomplished via the routes shown in Charts 2 and 3, respectively. Melting points and NMR data of the synthesized coumarins (4 and 5) and of related coumarins (5-methoxysuberenon, toddalenone, and Reisch's coumarin) are given in Table I, suggesting that so-called Reisch's coumarin might be 4.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）