5-Lipoxygenase Inhibitors Isolated from the Mushroom Boletopsis leucomelas (PERS.) FAYOD

Akira TAKAHASHI; Rie KUDO; Genjiro KUSANO; Shigeo NOZOE

doi:10.1248/cpb.40.3194

Akira TAKAHASHI, Rie KUDO, Genjiro KUSANO, Shigeo NOZOE

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Keywords: 5-lipoxygenase inhibitor, mushroom, basidiomycete, Boletopsis leucomelas, cycloleucomelone-leucoacetate

JOURNAL FREE ACCESS

1992 Volume 40 Issue 12 Pages 3194-3196

DOI https://doi.org/10.1248/cpb.40.3194

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Abstract

Terphenyl compounds, tentatively named Bl-I (1), Bl-II (2), Bl-III (3), Bl-IV (4) and Bl-V (5), showing 5-lipoxygenase inhibitory activity have been isolated from the mushroom Boletopsis leucomelas (PERS.) FAYOD. On the basis of physico-chemical and spectral evidence, they were concluded to be a series of cycloleucomeloneleucoacetates.

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