Agelasine G, a New Antileukemic Alkaloid from the Okinawan Marine Sponge Agelas sp.

Keisuke ISHIDA; Masami ISHIBASHI; Hideyuki SHIGEMORI; Takuma SASAKI; Jun'ichi KOBAYASHI

doi:10.1248/cpb.40.766

Keisuke ISHIDA, Masami ISHIBASHI, Hideyuki SHIGEMORI, Takuma SASAKI, Jun'ichi KOBAYASHI

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Keywords: sponge, Agelas sp., Agelasiidae, bromopyrrole, diterpene, 9-methyladenine, cytotoxicity

JOURNAL FREE ACCESS

1992 Volume 40 Issue 3 Pages 766-767

DOI https://doi.org/10.1248/cpb.40.766

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Abstract

A new antileukemic alkaloid, agelasine G (1a), has been isolated from the Okinawan marine sponge Agelas sp. and its structure elucidated to be a bromopyrrole alkaloid containing 9-methyladenine and diterpene moieties on the basis of the spectroscopic data.

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