Isolation of 6, 7-Demethylenedesoxypodophyllotoxin from Hernandia ovigera

Chihiro ITO; Takuya MATSUI; Tian-Shung WU; Hiroshi FURUKAWA

doi:10.1248/cpb.40.1318

Chihiro ITO, Takuya MATSUI, Tian-Shung WU, Hiroshi FURUKAWA

Author information

Keywords: Hernandia ovigera, Hernandiaceae, 6, 7-demethylenedesoxypodophyllotoxin, podophyllotoxin, lignan, ^<13>C-NMR, ^1H-NMR

JOURNAL FREE ACCESS

1992 Volume 40 Issue 5 Pages 1318-1321

DOI https://doi.org/10.1248/cpb.40.1318

Details

Abstract

6, 7-Demethylenedesoxypodophyllotoxin (1) was isolated from the seeds of Hernandia ovigera L. (Hernandiaceae) collected in Taiwan, together with several known lignans. This is the first example of the occurrence of 1 in a natural source. The assignments of the ¹³C-nuclear magnetic resonance signals of several podophyllotoxin analogues isolated from this plant were also established by means of two-dimensional H-C correlation spectroscopy (COSY) and H-C long range COSY techniques.

Corresponding author

Register with J-STAGE for free!