Platelet Aggregation Inhibitors from Populus sieboldii MIQUEL

Kiyomi KAGAWA; Katsuya TOKURA; Kiyohisa UCHIDA; Hisato KAKUSHI; Tsutomu SHIKE

doi:10.1248/cpb.40.2191

香川清水, 十倉一也, 内田清久, 嘉久志寿人, 四家勉

著者情報

キーワード: Populus sieboldii, Salicaceae, pyrocatechol, salicyl alcohol, platelet aggregation inhibitor

ジャーナルフリー

1992 年 40 巻 8 号 p. 2191-2192

DOI https://doi.org/10.1248/cpb.40.2191

詳細

抄録

The water extract of Populus sieboldii MIQUEL (Salicaceae) inhibited arachidonic acid-induced platelet aggregation. Pyrocatechol and salicyl alcohol were isolated as active constituents. Pyrocatechol showed an inhibitory effect on platelet aggregation induced by arachidonic acid with IC₁₀₀ value of 4μM, which was 25 times more potent than aspirin.

責任著者(Corresponding author)

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