Influence of Melatonin on Reproductive Behavior in Male Rats

Kenji YAMADA; Kazuyasu MARUYAMA; Satoru MOGAMI; Naonori MIYAGAWA; Minoru TSUBOI

doi:10.1248/cpb.40.2222

Kenji YAMADA, Kazuyasu MARUYAMA, Satoru MOGAMI, Naonori MIYAGAWA, Minoru TSUBOI

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Keywords: melatonin, reproductive behavior, male rat, copulation

JOURNALS FREE ACCESS

Volume 40 (1992) Issue 8 Pages 2222-2223

DOI https://doi.org/10.1248/cpb.40.2222

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Abstract

The influence of melatonin on reproductive behavior was examined by administering it to pinealectomized male rats for 30 consecutive days. After the 30-d administration of melatonin or vehicle, each male rat was introudced into a female rat's cage on the day of proestrus and allowed to mate overnight. All rats administered the vehicle and the pinealectomized rats copulated; five of the twelve melatonin (8.0 mg/kg)-treated rats did not copulate. These findings suggest that melatonin inhibits the reproductive behavior of male rats.

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