Antisweet Natural Products. VII. Hodulosides I, II, III, IV, and V from the Leaves of Hovenia dulcis THUNB.

Abstract

From the fresh leaves of Hovenia dulcis THUNB., five new dammarane glycosides named hodulosides I-V (1-5)were isolated besides the khown saponins hovenoside I (6), saponins C₂, (7), E (8) and H (9) and jujuboside B (10).Their structures were determined on the basis of chemical and spectral evidence. Further nuclear magnetic resonance spectral analysis of neohesperidosyl moieties of 1 led to the conclusion that the reported shifts of C₂ and C₃ of the glucosyl part in neohesperidose should be revised. All of the compounds (1-10) showed antisweet activities.