Three Glycosphingolipids Having the Phosphocholine Group from the Crude Drug "Jiryu" (The Earthworm, Pheretima asiatica)

抄録

Three glycosphingolipids were isolated in the pure state from the crude drug, "Jiryu" (the earthworm, Pheretima asiatica). Their structures were determined as N-docosanoyl-1-O-[6-O-(2-trimethylammonioethoxy)phosphinato-β-D-galactopyranosyl]-(4E)-16-methylheptadecasphingenine (1), N-docosanoyl-1-O-[6-O-(2-trimethylammonioethoxy)-phosphinato-β-D-galactopyranosyl]-(4E)-sphingenine (2) and N-tetracosanoyl-1-O-[6-O-(2-trimethylammonioethoxy)-phosphinato-β-D-galactopyranosyl]-(4E)-sphingenine (3). They are zwitterionic glycosphingolipids having a phosphocholine group attached to the sugar moiety, resembling those obtained from two kinds of marine annelid, and one has a branched long-chain base.