Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Fungal Metabolites. IX. Synthesis of a Membrane-Modifying Peptide, Hypelcin A-III, from Hypocrea peltata
松浦 耕司/ 飯田 彰長岡 康夫高石 喜久藤多 哲朗Tetsuro FUJITA
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1993 年 41 巻 11 号 p. 1955-1959

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A membrane-modifying peptide antibiotic having uncoupling activity on rat liver mitochondria, hypelcin A-III, has been synthesized by assembling five peptide fragments via the N, N'-dicyclohexylcarbodiimide method. The synthesized hypelcin A-III was identical with the natural product.

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© The Pharmaceutical Society of Japan
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