New Sesterterpenes with Nerve Growth Factor Synthesis-Stimulating Activity from the Okinawan Marine Sponge Hyrtios sp.

Yukiko DOI; Hideyuki SHIGEMORI; Masami ISHIBASHI; Fumio MIZOBE; Akira KAWASHIMA; Shiro NAKAIKE; Jun'ichi KOBAYASHI

doi:10.1248/cpb.41.2190

土居由貴子, 繁森英幸, 石橋正己, 溝部文夫, 川嶋朗, 中池司郎, 小林淳一

著者情報

キーワード: sesterterpene, nerve growth factor, sponge, 12-O-desacetylfuroscalarol, 12-O-desacetylscalarin, Hyrtios sp.

ジャーナルフリー

1993 年 41 巻 12 号 p. 2190-2191

DOI https://doi.org/10.1248/cpb.41.2190

詳細

抄録

Two new pentacyclic sesterpenes, 12-O-desacetylfuroscalarol (1) and 12-O-desacetylscalarin (2), which enhance nerve growth factor synthesis, have been isolated from the Okinawan marine sponge Hyrtios sp. and their structures elucidated on the basis of spectroscopic data.

責任著者(Corresponding author)

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