Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Revised Structure and Stereochemistry of Hypothemycin
Tsutomu AGATSUMA, Akira TAKAHASHI, Chizuko KABUTO, Shigeo NOZOE
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Keywords: hypothemycin, revised structure, 2D-NMR, X-ray crystallographic analysis, Coriolus versicolor, Hypomyces trichothecoides
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1993 Volume 41 Issue 2 Pages 373-375

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Abstract
A cytotoxic 14-membered resorcylic macrolide, isolated from Coriolus versicolor (L. : FR.) QUEL., was found to be identical with hypothemycin, previously isolated from Hypomyces trichothecoides TSUBAKI. The structure of hypothemycin has been elucidated to be 1 rather than the originally proposed 2.
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© The Pharmaceutical Society of Japan
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