STRUCTURE OF ACRIGNINE-A, THE FIRST NATURALLY OCCURRING ACRIDONOLIGNOID FROM CITRUS PLANTS

Yuko TAKEMURA; Masami ABE; Motoharu JU-ICHI; Chihiro ITO; Keiichiro HATANO; Mitsuo OMURA; Hiroshi FURUKAWA

doi:10.1248/cpb.41.406

Yuko TAKEMURA, Masami ABE, Motoharu JU-ICHI, Chihiro ITO, Keiichiro HATANO, Mitsuo OMURA, Hiroshi FURUKAWA

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Keywords: acridonolignoid, acridone, Citrus, acrignine-A, crystal structure, lignoid

JOURNAL FREE ACCESS

1993 Volume 41 Issue 2 Pages 406-407

DOI https://doi.org/10.1248/cpb.41.406

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Abstract

The chemical structure of acrignine-A (1), an acridone alkaloid carrying lignan moiety, from roots of Citrus plants (Rutaceae) have been elucidated by spectrometric studies using ¹H-¹³C long-range COSY and NOE experiments. The structure was confirmed by single crystal X-ray analysis. This is the first example of an acridonolignoid isolated from natural sources.

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