Synthesis, Structural and Biological Studies of Nickel(II), Copper(II) and Zinc(II) Chelates with Tridentate Schiff Bases Having NNO and NNS Donor Systems

Abstract

New tridentate pyrimidine-derived NNO and NNS donor Schiff base ligands and their nickel(II), copper(II) and zinc(II) chelates have been synthesized and characterized on the basis of elemental analysis, ¹H-NMR, IR and electronic spectral data and conductance and magnetic measurements. The synthesized ligands and their metal chelates have been screened and compared for their antibacterial action against bacterial species Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae.