Preparation and Evaluation of Free Oxygen Absorber in Pharmaceutical Preparations

Sompol PRAKONGPAN; Wiriya LIMCHALERM; Tsuneji NAGAI

doi:10.1248/cpb.41.983

Sompol PRAKONGPAN, Wiriya LIMCHALERM, Tsuneji NAGAI

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Keywords: free oxygen absorber, ion(II) compound, oxygen removal, chemical kinetics, iron-oxygen, deoxygenator

JOURNAL FREE ACCESS

1993 Volume 41 Issue 5 Pages 983-985

DOI https://doi.org/10.1248/cpb.41.983

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Abstract

Ferrous compound was used as a free oxygen absorber (FOA). It was prepared from the chemical reaction of ferrous sulfate and sodium hydroxide under nitrogen atmosphere. The condition of reaction was investigated to obtain a product of high absorbing activity. A kinetic study was done when FOA was exposed to the air and the efficacy was tested.

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