1994 Volume 42 Issue 10 Pages 2161-2163
Cryptocaryalactone, a 1, 3-polyol-derived α, β-unsaturated δ-lactone, has been synthesized in a stereocontrolled manner via the coupling reaction of a chiral dithiane with an epoxide and anti-stereoselective 1, 3-asymmetric reduction of the derived hydroxy ketone.