Author's Organization：Laboratoire de Chimie Organique, Institut des Sciences Pharmaceutiques et Biologiques Laboratoire de Chimie Organique, Institut des Sciences Pharmaceutiques et Biologiques Laboratoire de Chimie Organique, Institut des Sciences Pharmaceutiques et Biologiques
Published: November 15, 1994Received: April 27, 1994Available on J-STAGE: March 31, 2008Accepted: June 10, 1994
Advance online publication: -
Revised: -
The nucleophilic addition of dimethylamine to bromojuglones and bromomethyljuglones is followed by elimination of hydrogen bromide or oxidation. With 2-bromojuglone, the oxidative process predominates at low temperature. The regiochemistry of the addition is a function of the temperature and of the position of the bromine atom (C-2 or C-3) on the quinone.
