Lipid A and Related Compounds. XXIX. Synthesis of Biologically Active N-Acylated L-Asparagine-Containing D-Glucosamine Derivatives Structurally Related to Lipid A

Yoshitomo SUHARA; Misa ARAKAWA; Kiyoshi IKEDDA; Kazuo ACHIWA

doi:10.1248/cpb.42.2526

須原義智, 荒川美佐, 池田潔, 阿知波一雄

著者情報

キーワード: D-glucosamine-asparagine compound, N-acylated L-aspartic acid, lipid A analog, glucosylamine, mitogenic activity, nitric oxide productivity

ジャーナルフリー

1994 年 42 巻 12 号 p. 2526-2531

DOI https://doi.org/10.1248/cpb.42.2526

詳細

抄録

New β-N-acylated L-asparagine-linked D-glucosamine derivatives, in which the reducing unit of lipid A has been mimicked by a lipoamino acid, have been synthesized. Compounds 1 and 2 exhibit mitogenicity and nitric oxide (NO) productivity.

責任著者(Corresponding author)

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