Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Bitetrahydroanthracenes from Flowers of Cassia torosa CAV.
Susumu KITANAKAMichio TAKIDO
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JOURNAL FREE ACCESS

1994 Volume 42 Issue 12 Pages 2588-2590

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Abstract

A new bitetrahydroanthracene derivative, torosaol-III, was isolated from the flowers of Cassia torosa CAV. along with physcion, 5, 7'-physcionanthrone-physcion, 5, 7'-biphyscion, torosanin-9, 10-quinone, 5, 7-dihydroxychromone, naringenin, and chrysoeriol. The structure of torosaol-III was established as 3, 3', 4, 4'-tetrahydro-3, 3', 8, 8', 9, 9'-hexahydroxy-6, 6'-dimethoxy-3, 3'-dimethyl-1(2H), 1'(2H)-5, 7'-bianthracenone on the basis of spectral and chemical evidence. Dimeric tetrahydroanthracenes exhibited cytotoxic activity against KB cells in the tissue culture.

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© The Pharmaceutical Society of Japan
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