Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Fundamental Study on the Evaluatoin of Strength of Granular Particles
Kazumi DANJOHironobu KATOAkinobu OTSUKAKouichi USHIMARU
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1994 Volume 42 Issue 12 Pages 2598-2603

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Abstract
Compaction mechanisms and the strength required for compacting granular particles are considered to be influenced by granular particle strength. A fundamental study evaluating the crushing strength of particles by various methods was performed, and value obtained by the various methods were compared. Firstly, the particle diameter and crushing load for 140 particles were measured individually, and the single particles strength (σg) was calculated. The crushing strength exponentially decreased with an increase in particle diameter up to about 500 μm, and thereafter showed a constant value.Next, the compression of multiple particles was measured. A linear relationship existed between the crushing load and the number of particles, and the average particle strength (σ^^-g) was found to be lower than σg in every sample. This may be due to a variety of factors such as the distribution of particle diameter, shape, and crushing strength in multiple particles.Finally, compaction tests of the particle bed were performed, and the parameters of some compression equations, which were recognized as values related to the particle strength were determined. The inflection points of the compression curve were also examined. The strength obtained from the first inflection point appeared to be in fairly good agreement with σ^^-g.
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© The Pharmaceutical Society of Japan
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