Studies on Active Substances in Herbs Used for Hair Treatment. I. Effects of Herb Extracts on Hair Growth and Isolation of an Active Substance from Polyporus umbellatus F.

Yasunori INAOKA; Akemi SHAKUYA; Hirotatsu FUKAZAWA; Hitoshi ISHIDA; Haruo NUKAYA; Kuniro TSUJI; Hideo KURODA; Masanori OKADA; Makoto FUKUSHIMA; Takuo KOSUGE

doi:10.1248/cpb.42.530

Yasunori INAOKA, Akemi SHAKUYA, Hirotatsu FUKAZAWA, Hitoshi ISHIDA, Haruo NUKAYA, Kuniro TSUJI, Hideo KURODA, Masanori OKADA, Makoto FUKUSHIMA, Takuo KOSUGE

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Keywords: herb, Polyporus umbellatus, 3, 4-dihydroxybenzaldehyde, C₃H/He mice

JOURNAL FREE ACCESS

1994 Volume 42 Issue 3 Pages 530-533

DOI https://doi.org/10.1248/cpb.42.530

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Abstract

The effects of methanol extracts of 80 herbs on hair growth were investigated, using normal C₃H/He mice from which telogen hair on the back had been removed. Eighteen of the extracts apparently promoted hair regrowth on the mice. As one of active principles in Polyporus umbellatus F., 3, 4-dihydroxybenzaldehyde was isolated by column chromatography on Amberlite XAD-2, Sephadex LH-20 and silica gel.

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