Preparation of 2-Aminooxyethyliminodiacetic Acid, a Bifunctional Chelating Agent for Carbonyl Labeling

Abstract

2-Aminooxyethyliminodiacetic acid, designed as a possible bifunctional chelating agent with a hydroxylamino group that can bind a carbonyl group of biomolecules, was synthesized by three different methods. Its oxime derivatives with some carbonyl compounds were readily prepared.