Palladium-Catalyzed Intramolecular Metallo-Ene Reactions Using Allylic Sulfones as Enophiles

Kunio HIROI; Kazushige HIRASAWA

doi:10.1248/cpb.42.786

著者情報

キーワード: palladium catalyst, metallo-ene reaction, allylic acetate, allylic sulfone, sulfinate-sulfone rearrangement, stereoselectivity

ジャーナルフリー

1994 年 42 巻 4 号 p. 786-791

DOI https://doi.org/10.1248/cpb.42.786

詳細

抄録

Palladium-catalyzed intramolecular metallo-ene reactions were studied using allylic sulfones as enophiles. Palladium-catalyzed reactions of allylic acetates and methyl carbonates bearing allylic sulfones at appropriate sites were carried out in acetic acid at 80°C to give cyclized products, cyclohexane derivatives, with extremely high diastereoselectivity. The stereochemistry of these reactions was examined under various reaction conditions using several model compounds.

責任著者(Corresponding author)

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