Synthesis and Chemical Modification of 3, 3-Dimethyl-1H, 3H-furo[4, 3-b][1, 5]benzothiazepin-1-one

Keizo MATSUO; Masayo SUNAGO; Natsue OKUTANI; Tatsuko TAKAGI; Hiromi NAKAMOTO; Mariko KOBAYASHI

doi:10.1248/cpb.43.1643

著者情報

キーワード: 1H, 3H-furobenzothiazepin-1-one, [2+2]cycloaddition, 1, 3-dipolar cycloaddition, β-lactam, [1, 2, 4]oxadiazolo-fused heterocycle

ジャーナルフリー

1995 年 43 巻 10 号 p. 1643-1646

DOI https://doi.org/10.1248/cpb.43.1643

詳細

抄録

Heating of 3-(2-aminophenylthio)-2-methoxycarbonyl-4-methyl-2-penten-4-olide with triethylamine hydrochloride gave 3, 3-dimethyl-1H, 3H-furo[4, 3-b][1, 5]benzothiazepin-1-one. Some chemical modifications of the product including [2+2]cycloaddition and 1, 3-dipolar cycloaddition to the imino group in the product were performed.

責任著者(Corresponding author)

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