Abstract
An enzymatic method for preparation of the enantiomers of chiral diols 2a, b and their monoacetates 3a, b with 100% enantiomeric purity by using lipase-catalyzed esterification and/or hydrolysis was established, The (R)-enantiomers were more reactive in both acetylation of (±)-2a, b and hydrolysis of (±)-3a, b catalyzed by lipase OF-360 from Candida cylindracea.
