Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
ENANTIO- AND DIASTEREOCONTROLLED SYNTHESIS OF EPIBATIDINE ANALOGUES
Kou HIROYA, Koji UWAI, Kunio OGASAWARA
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Keywords: epibatidine, 7-azabicyclo[2.2.1]heptane, epibatidine analogue, enantiocontrolled synthesis
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1995 Volume 43 Issue 5 Pages 901-903

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Abstract
Three structural analogus of a potent non-opiate analgesic alkaloid epibatidine have been synthesized in optically pure forms in enantio- and diastereo-controlled ways using a chiral 2, 5-cyclohexadiene-1, 4-diol synthon.
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© The Pharmaceutical Society of Japan
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