Abstract
Nine new oleanate-type saponins, polygalasaponins XXXIII-XLI, along with seven known saponins were isolated from the roots of Polygala fallax HEMSL. Polygalasaponins XXXIII-XLI were elucidated as 3-O-β-D-glucopyranosyl presenegenin 28-O-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-(4-O-acetyl)-β-D-fucopyranosyl ester, 3-O-β-D-glucopyranosyl presenegenin 28-O-β-D-galactopyranosyl-(1→4)-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-(4-O-acetyl)-β-D-fucopyranosyl ester, 3-O-β-D-glucopyranosyl presenegenin 28-O-β-D-galactopyranosyl-(1→4)-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-(3, 4-di-O-acetyl)-β-D-fucopyranosyl ester, 3-O-β-D-glucopyranosyl presenegenin 28-O-β-D-galactopyranosyl-(1→4)-β-D-xylopyranosyl-(1→4)-[(5-O-acetyl)-β-D-apiofuranosyl-(1→3)]-α-L-rhamnopyranosyl-(1→2)-(3, 4-di-O-acetyl)-β-D-fucopyranosyl ester, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl presenegenin 28-O-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-(3-O-acetyl)-β-D-fucopyranosyl ester, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl presenegenin 28-O-β-D-galactopyranosyl-(1→4)-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-(4-O-acetyl)-β-D-fucopyranosyl ester, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl presenegenin 28-O-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→3)]-(4-O-acetyl)-β-D-fucopyranosyl ester, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl presenegenin 28-O-β-D-galactopyranosyl-(1→4)-β-D-xylopyranosyl-(1→4)-[β-D-apiofuranosyl-(1→3)]-α-L-rhamnopyranosyl-(1→2)-(3, 4-di-O-acetyl)-β-D-fucopyranosyl ester and 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl presenegenin 28-O-β-D-galactopyranosyl-(1→4)-β-D-xylopyranosyl-(1→4)-[(5-O-acetyl)-β-D-apiofuranosyl-(1→3)]-α-L-rhamnopyranosyl-(1→2)-(3, 4-di-O-acetyl)-β-D-fucopyranosyl ester, respectively, on the basis of spectroscopic and chemical evidence.
