Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Marine Natural Products. XXXVI. Biologically Active Polyacetylenes, Adociacetylenes A, B, C, and D, from an Okinawan Marine Sponge of Adocia sp.
Motomasa KOBAYASHITaifo MAHMUDHisashi TAJIMAWeiqi WANGShunji AOKIShinsaku NAKAGAWATadanori MAYUMIIsao KITAGAWA
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1996 Volume 44 Issue 4 Pages 720-724

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Abstract
Adociacetylenes A (1), B (2), C (3), and D (4) were isolated as new polyacetylenes from an Okinawan marine sponge of Adocia sp. Their chemcial structuers have been elucidated on the bases of their chemcial and physico-chemical properties. Adociacetylenes A (1), B (2), C (3), and D (4) exhibited inhibitory activity in the in vitro endothelial cell-neutrophil leukocyte adhesion assay.
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© The Pharmaceutical Society of Japan
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