Monoamine Oxidase-Inhibitory Components from an Ascomycete, Coniochaeta tetraspora

Abstract

Two cyclopentabenzopyran-4-ones tentatively named CT-2 and -3 have been isolated as new monoamine oxidase (MAO)-inhibitory components from an Ascomycete, Coniochaeta tetraspora, together with a new chlorinated pigment tentatively named CT-1. The structures of CT-2 and -3 have been elucidated, and these products were shown to be identical with coniochaetones A and B, respectively, which have recently been isolated as antifungal components from Coniochaeta saccardoi. CT-1 appears to be a seco-anthraquinone.