Studies on Nepalese Crude Drugs. XXIII. On the Diterpenoid Constitutents of the Aerial Parts of Scutellaria grossa WALL.
1997 Volume 45 Issue 6 Pages 1097-1100
Details
1997 Volume 45 Issue 6 Pages 1097-1100
From the aerial parts of Scutellaria grossa, a new neoclerodane diterpene named scutegrossin A has been isolated together with five known neoclerodane diterpenes, jodrellin B, scutecolumnin A, scutalsin, scutecyprol B and scutalbin B.The strucure of a new compound has been determined by spectroscopic and chemical methods as (11S, 13S, 16S, 19R)-6α-O-acetyl-19-O-[(E)-2-methyl-2-butenoyl]-2α, 19;4α, 18;11, 16;15, 16-tetraepoxy-14-neoclerodene-6, 19-diol.In addition, the absolute stereochemistry of 2-methylbutanoyl group of scutecolumnin A and scutalbin B has been ascertained to be the S form.
