Enantiomer-Differentiating Ability of Cyclo(L-Phe-L-Pro)4 Having a Rigid Skeleton for Phenylalanine Methylester Hydrochloride
1997 年 45 巻 7 号 p. 1202-1204
詳細
1997 年 45 巻 7 号 p. 1202-1204
The formation constant of the 1 : 1 complex of cyclo(L-Phe-L-Pro)4 (1) with L-PheOMe·HCl was about 13.2 times that of the complex with D-PheOMe·HCl. The 1 : 1 complex of 1 with L-PheOMe·HCl formed three intermolecular hydrogen bonds between Pro2 CO, Phe1 CO and the amino group, and Phe2 NH and the carbonyl group, whereas that with D-PheOMe·HCl formed only one between Phe1 CO and the amino group.
