N-[2-(1-AZABICYCLO[3.3.0]OCTAN-5-YL)ETHYL]-2-NITROANILINE, A POTENT MUSCARINIC AGONIST

Tomoo SUZUKI; Mituru OKA; Kouji MAEDA; Kenichi FURUSAWA; Takahiko MITANI; Tadashi KATAOKA

doi:10.1248/cpb.45.1218

Tomoo SUZUKI, Mituru OKA, Kouji MAEDA, Kenichi FURUSAWA, Takahiko MITANI, Tadashi KATAOKA

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Keywords: muscarine receptor agonist, SK-946, 1-azabicyclo[3.3.0]octane

JOURNAL FREE ACCESS

1997 Volume 45 Issue 7 Pages 1218-1220

DOI https://doi.org/10.1248/cpb.45.1218

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Abstract

The muscarine receptor agonist SK-946, and aniline derivative with a characteristic bicyclo amine, was found. We describe a new synthetic method for 1-azabicyclo[3.3.0]octane and describe the biological activity of SK-946.

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