Abstract
Four new sesquiterpenoid derivatives, 1-(2, 4-dihydroxyphenyl)-2-hydroxy-5, 9, 13-trimethyl-4(E), 8(E), 12-tetradecartien-1-one, 1-(2, 4-dihydroxyphenyl)-3, 7, 11-trimethyl-3-vinyl-6-(E), 10-dodecadiene-1-one, 1-(2, 4-dihydroxyphenyl)-3, 7, 11-trimethyl-3-vinyl-6(E), 10-dodecadiene-1, 9-dione and 1-(2, 4-dihydroxyphenyl)-3, 7-dimethyl-3-vinyl-8-(4-methyl-2-furyl)-6(E)-octen-1-one, were isolated from roots of Ferula ferulioides. The structures of these new compounds were establiished by comprehensive spectral analysis. The biosynthetic pathway leading to these compounds is proposed based on their structures.