Studies on the Constituents of Cimicifuga Species. XXI. Two New Cyclolanostanol Xylosides, Bugbanosides A and B from Cimicifuga simplex WORMSK.

Abstract

Two new cyclolanostanol xylosides, bugbanosides A and B, were isolated from the underground parts of Cimicifuga simplex WORMSK. (Ranunculaceae). Bugbanosides A and B were formulated as 20(R), 23(R), 24(R), 25(S), 26(S and R)-16β, 23 : 23, 26 : 24, 25-triepoxy-1α, 3β, 26-trihydroxy-9, 19-cyclolanost-7-ene 3-O-β-D-xylopyrano-side and 20(R), 23(R), 24(R), 25(S), 26(S and R)-16β, 23 : 23, 26 : 24, 25-triepoxy-1α, 3β, 26-trihydroxy-9, 19-cyclo-lanostane 3-O-β-D-xylopyranoside respectively, by spectroscopic and chemical methods.