Synthesis of Four Possible Intermediates after Secologanin on the Biosynthesis of the Oleoside-, 10-Hydroxyoleoside- and Ligustaloside-Type Glucosides in Oleaceous Plants

Abstract

To examine the biosynthetic pathway from secologanin to three types of secoiridoid glucosides characteristic of oleaceous plants, synthesis of two respective stereoisomers at C-8 of 8, 10-epoxysecologanin and -secoxyloganin was established and their deuterium-labeled analogues were prepared.