First Synthesis of Neoalangiside, a New Tetrahydroisoquinoline-monoterpene Glucoside with Oxygen Functions at Unusual C1, C2 Positions

Abstract

The novel structure of neoalangiside, a new tetrahydroisoquinoline-monoterpene glucoside carrying oxygen functions at the unusual C1 and C2 positions, was confirmed by chemical synthesis starting from isovanillin and secologanin.