Abstract
Twelve new cyclolanostanol glycosides (1-12) were isolated from the underground parts of Cimicifuga simplex WORMSK. (Ranunculaceae) together with five known cyclolanostanol glycosides (13-17). On the basis of spectral and chemical evidence, the structures of 1-12 were determined to be 24-epi-24-O-acetyl-7, 8-didehydrohydroshengmanol 3-O-β-D-xylopyranoside and 3-O-α-L-arabinopyranoside, 24-O-acetyl-7, 8-didehydrohydroshengmanol 3-O-β-D-xylopyranoside and 3-O-α-L-arabinopyranoside, 7, 8-didehydrocimigenol 3-O-β-D-xylopyranoside and 3-O-α-L-arabinopyranoside, 25-O-acetyl-7, 8-didehydrocimigenol 3-O-β-D-xylopyranoside and 3-O-α-L-arabinopyranoside, 1α-hydroxycimigenol 3-O-α-L-arabinopyranoside and 3-O-β-D-galactopyranoside, 23-O-acetyl-7, 8-didehydroshengmanol 3-O-β-D-galactopyranoside, and 26-deoxycimicifugoside, respectively. The last compound (12) was also obtained from the underground parts of Actaea asiatica HARA (Ranunculaceae).
